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BrIC lab in collaboration with Invent Lab awarded NCI ITCR U01 grant

BrIC in collaboration with Invent lab were recently awarded a NCI U01 grant for their project " RadxTools for assessing tumor treatment response on imaging".  The collaborative team will be developing new radiomics and AI tools to improve treatment for patients, allowing more precise understanding and prognosis of post-treated lesions.

BrIC lab paper accepted at Radiology-AI

Ruchika's paper entitled "Tumor-habitat Derived Radiomic Features on Pre-treatment MRI that are Prognostic of Progression-free Survival in Glioblastoma are Associated with Key Morphologic Attributes on Histopathology: A Feasibility Study", got accepted at Radiology-AI. Congrats, Ruchika!

Niha has defended her Ph.D. thesis.

Congrats to Niha for successfully defending her Ph.D. thesis. Great job, Niha!

Pallavi named a JNJInnovation Women in STEM2D Scholar

Congratulations to Pallavi who was named a Johnson and Johnson Innovation Women in STEM2D Scholar for her research to address critical complications in brain tumors.

BrIC lab paper accepted at MICCAI 2020

Marwa's paper entitled "Spatial-And-Context aware (SpACe) "virtual biopsy'' radiogenomic maps to target tumor mutational status on structural MRI", got accepted in MICCAI 2020 conferecne. Congrats, Marwa!

BrIC lab paper awarded the "Most cited paper award 2017"

BrIC lab paper entitled "Radiomic features from the peritumoral brain parenchyma on treatment-naïve multi-parametric MR imaging predict long versus short-term survival in glioblastoma multiforme: Preliminary findings", was published in European Radiology in 2017, and has received 57 citations in the two years following publication (2018-2019). It was, therefore, awarded a "Most Cited Paper Award 2017" for receiving the second highest number of citations.

BrIc lab awarded the prestigious V Foundation Award

BrIC lab in collaboration with Cleveland Clinic was awarded a 3-year V Foundation Translational Award for their work on capturing tumor heterogeneity on post-treatment MRIs. 

Niha Beig to serve term as Trainee Editorial Board member for journal Radiology: Artificial Intelligence...

Niha has been selected for a one-year term as a Trainee Editorial Board member for the journal Radiology: Artificial Intelligence.

Dr. Tiwari to give 3 Keynote talks at MICCAI workshops

Dr. Tiwari will be giving 3 keynotes talks at 3 different workshops at MICCAI this year. On 13th October, she will talk at AI in neuro-oncology workshop, while on the 17th, she will be presenting BrIC lab's work at the Medical Image Learning with Less Labels and Imperfect Data Workshop and BrainLes workshop. 

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Dr. Tiwari is an Invited speaker at SNO METS meeting

Dr. Tiwari will be presenting BrIC lab's work on differentiating radiation effects from tumor recurrence in Metastatic Brain Tumors using radiomic analysis.  

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Dr. Tiwari participated in inaugural Young Investigators Forum in Neuro-Oncology.

Dr. Tiwari participated as one of 40 young investigators in the inaugural 2019 Young Investigators Forum in Neuro-Oncology held in Atlanta.

BrIC’s lab paper recognized as being the 2019 9th most cited article

The European Society of Radiology (ESP) Board of Directors and the European Radiology editorial team recognized researchers in the Center for Computational Imaging and Personalized Diagnostics and their co-authors on their October 2017 article being the ninth most cited according to the recent impact factor calculations.

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Ramon Correa successfully defended his Master’s thesis

Congratulations Ramon! Ramon will be starting his PhD in Computer Science at Emory University in Fall 2019. 

Bolin Song successfully defended his master's thesis.

Congratulations Bolin! Bolin will start his PhD at the Center for Computational Imaging and Personalized Diagnostics at Case Western Reserve University in Fall 2019. 

BrIC lab's work featured on the December cover of AJNR

Work by Research Associate, Marwa Ismail, in the Brain Image Computing (BrIC) Laboratory was featured on the cover of the December 2018 issue of the American Journal of Neuro-radiology. The work was led by Dr. Pallavi Tiwari, assistant professor of Biomedical Engineering, and was performed in collaboration with Cleveland Clinic and Brigham and Women's Hospital. 

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BrIC lab's work featured on CDMRP website

BrIC lab's work on predicting response to chemo-radiation treatment in brain tumors funded through the Department of Defense Career Development Award has been highlighted on the CDMRP website. 

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Pallavi selected as Crains Cleveland's Forty under 40

Dr. Pallavi Tiwari has been selected as one of the recipients of Crains Cleveland Forty under 40 for 2018. She will be facilitated along with the other honorees in an event on November 19th. 

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Niha wins the RSNA research trainee award

Congrats to Niha for winning the RSNA research trainee award! Niha will be presenting her work on "Probabilistic Atlases of pre-treatment MRI reveal hemispheric and love specific spatial distributions across molecular sub-types of diffuse Gliomas" at RSNA 2018. 

Manuscript accepted in AJNR

BrIC lab's paper on Shape features of the lesion habitat to differentiate tumor progression from pseudo-progression on multi-parametric MRI has been accepted for publication in AJNR. Pre-print will be out soon.

BrIC lab awarded 3 year Department of Defense PCRP grant in brain tumors

Dr. Tiwari's proposal on developing a Systems Biology Approach to Predicting and Assessing Response to Chemo-radiation for Brain Tumors has been recommended for funding through the PCRP Department of Defense mechanism. The 3 year grant was awarded to Dr. Tiwari as an early career investigator through the CDMRP/DOD's Peer Reviewed Cancer Program (PCRP) mechanism.

Congrats to Niha for winning travel scholarship to Grace Hopper conference

Congrats to Niha who won the grace hopper scholarship to attend the conference later this year in Houston. 

Abstract accepted at RSNA

Congrats to Niha and Marwa! Their joint work titled "Probabilistic Atlases of Pre-Treatment MRI Reveal Hemispheric and Lobe-Specific Spatial Distributions across Molecular Sub-Types of Diffuse Gliomas" has been accepted for presentation at RSNA 2018. 

BrIC lab's work featured in AJNR digest

BrIC lab's work on using radiomics for distinguishing radiation necrosis from cancer recurrence is featured in the March-April 2018 AJNR News Digest. 

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Congrats to Prateek on winning the doctoral excellence award

Congrats to Dr. Prateek Prasanna who successfully defended his thesis in May 2017. Prateek was also the recipient of the competitive 2017 Doctoral Excellence Award awarded by the School of Medicine, Case Western Reserve University. 

Manuscript accepted in Nature Scientific Reports

Our paper titled "Radiogenomic analysis of hypoxia pathway is predictive of overall survival in Glioblastoma" has been accepted for publication in Nature Sci Reports. Pre-print will out be soon.

BrIC lab awarded Dana Foundation David Mahoney Grant

BrIC lab in collaboration with Dr. Jennifer Yu at Cleveland Clinic was awarded the 2017 Dana Foundation David Mahoney Neuroimaging Award for evaluating our CoLlAGe radiomic feature in distinguishing radiation effects from tumor recurrence in brain metastasis patients. 

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BrIC lab's technology NeuroRadVision recognized by the State of Ohio

A team of biomedical engineering researchers earned official commendations from the State of Ohio for its first-place finish in the collegiate division at the inaugural Medical Capital Innovation Competition earlier this year. The team consisted of Prateek Prasanna, a recent biomedical engineering graduate, Anant Madabhushi, the F. Alex Nason II Professor of Biomedical Engineering, and was led by Pallavi Tiwari, assistant professor of biomedical engineering. The team received official notes of congratulations from the General Assembly of the State of Ohio and from Ohio Secretary of State Jon Husted. 

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Abstracts accepted at RSNA and SNO 2017

Congrats to Marwa for her abstract that got accepted as an oral presentation at RSNA in November this year. Congrats also to Prateek, Marwa, and Ayush for their abstracts to be presented at SNO later this year. 

BRIC lab's AJNR paper got nominated for the annual Lucien Levy Best Research Article Award

Our AJNR paper titled  “Computer-Extracted Texture Features to Distinguish Cerebral Radionecrosis from Recurrent Brain Tumors on Multiparametric MRI: A Feasibility Study” was one of the nominees for the annual Lucien Levy Best Research Article Award. This award is named for the late AJNR Senior Editor who championed its establishment and recognizes the best original research paper accepted by the American Journal of Neuroradiology in 2016. The article was selected by a vote of the Journal’s Editor-in-Chief and Senior Editors. An announcement including the nomination is posted on the AJNR Web site.

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NeuroRadVision chosen to present at Ohio Collegiate Venture Showcase

A team of biomedical engineers at Case Western Reserve University, is among seven of 23 research teams from the 2016 I-Corps@Ohio program selected to present their new technology in brain tumor treatment management, NeuroRadVision, to potential investors at the upcoming Ohio Collegiate Venture Showcase.

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Pallavi's interview on the recently published AJNR article

Pallavi's interview on the recently published AJNR paper on distinguishing radiation necrosis from tumor recurrence using radiomic analysis is published in

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Congrats to Niha on acceptance of her SPIE paper!

Congrats to Niha whose paper on radiogenomics for predicting GBM survival got accepted in SPIE 2016 as an oral presentation. 

"New computer program beats physicians at brain cancer diagnoses, could eliminate costly and risky brain biopsies"

Computer programs have defeated humans in Jeopardy!, chess and Go. Now a program developed at Case Western Reserve University has outperformed physicians on a more serious matter. The program was nearly twice as accurate as two neuroradiologists in determining whether abnormal tissue seen on magnetic resonance images (MRI) were dead brain cells caused by radiation, called radiation necrosis, or if brain cancer had returned.

The direct comparison is part of a feasibility study published in the American Journal of Neuroradiology today.

“One of the biggest challenges with the evaluation of brain tumor treatment is distinguishing between the confounding effects of radiation and cancer recurrence,” said Pallavi Tiwari, assistant professor of biomedical engineering at Case Western Reserve and leader of the study. “On an MRI, they look very similar.” 

The news release was covered on,,,, and  several other websites. 

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BrIC lab's paper on distinguishing radiation necrosis from tumor recurrence in online!

Our paper titiled Computer-Extracted Texture Features to Distinguish Cerebral Radionecrosis from Recurrent Brain Tumors on Multiparametric MRI: A Feasibility Study is now online. The co-authors on this paper include Case School of Engineering’s Anant Madabhushi, Director, Center for Computational Imaging and Personalized Diagnostics; Prateek Prasanna, PhD student; and Gagandeep Singh, MBBS, medical research fellow; Case Western Reserve School of Medicine’s Leo Wolansky, MD, professor of radiology; Mark Cohen, MD, professor of pathology; Ameya Nayate, assistant professor of radiology; Amit Gupta, Fellow, Nuclear Radiology, University Hospitals Case Medical Center; Andrew Sloan, MD, Peter D. Cristal Chair of Neurosurgical Oncology; and Lisa Rogers, DO, professor of neurology; and University of Texas Southwest Medical Center’s Marco Pinho, MD, assistant professor of radiology; and Kimmo Hattanpaa, MD, PhD associate professor of pathology.

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Niha wins travel award at Big Data neuroimaging conference

Congrats to Niha whose poster on radiogenomics analysis of GBM got selected for Travel Award at Cleveland Clinic Research Conference on "Challenges and Advances in Big Data in Neuroimaging". 

Three abstracts from BrIC lab accepted at SNO

Two of Niha's projects on radiogenomics for treatment response of brain tumors have been accepted for oral presentations in the neuroimaging session at the SNO conference in November. BrIC lab will also present a poster led by Marwa Ismail on distinguishing pseudo-progression from tumor recurrence at the SNO conference. 

Pallavi gave an invited talk at AAPM 2016 conference

Pallavi was an invited speaker at the special symposium on “State-of-the-Art in Radiomics in Radiology and Radiation Oncology”, organized under the AAPM 2016 conference in Washingon DC. Pallavi's talk was entitled "Radiomics, Radio-genomics, Radio-pathomics: Connecting the dots towards personalized medicine in Brain Tumors". 

4 abstracts from BrIC lab accepted at RSNA 2016

Congrats to Prateek and Jhimli whose abstracts in brain tumors and multiple sclerosis got accepted as oral presentations at RSNA 2016. Congrats also to Niha for her abstract in lung cancers (in collaboration with CCIPD) that got accepted for an oral presentation. A total of 9 abstracts were accepted from CCIPD and BrIC lab. 

4 abstracts from BrIC lab accepted at SNO 2016

4 Abstracts from BriC lab got accepted at the Society of Neuro-oncology (SNO) conference to be held at Scottsdale Arizona in November. Congrats to Prateek, Niha, and Jhimli. Dr. Tiwari will also be giving an invited lecture on laser-ablation treatment for Glioblastoma at the conference. 

Congrats to Prateek for securing 2nd price in Galen Competition

Congrats to Prateek Prasanna and Ahmad Algohary, graduate students at BrIC and CCIPD, for winning second place in the Galen competition for their business pitch on NeuroradVision - a toolkit for assessing treatment response on brain imaging. The team received a price money of $3,000 to continue translational efforts on the technology.

“Indian American Women Entrepreneurs & Philanthropists are Champions of Change in USA and India”

The new MRI-based technique to provide the patients of Glioblastoma Multiforme cancer with personalized therapy is based on her clinical findings that GBM is the most aggressive cerebral cancer and that less than 5% of all GBM patients survive more than over 5 years. A leading cancer researcher at Case Western Reserve University, Dr. Pallavi Tiwari found that only enhanced personalized therapy is the best solution to the failure of “one-size-fits-all treatment” for GBM patients.

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“Three university-based technologies secure translational state funding awards”

Pallavi Tiwari, assistant professor of biomedical engineering and an associate member of the Case Comprehensive Cancer Center, is leading the development of NeuroRadVision, imaging software that distinguishes between a recurrent brain tumor and benign effects of radiation, which can appear similar on a routine MRI scan, resulting in unnecessary surgeries. 

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